Article
Genomic Characterization of Neisseria gonorrhoeae Strains from 2016 U.S. Sentinel Surveillance Displaying Reduced Susceptibility to Azithromycin.
Antimicrobial agents and chemotherapy - 21 Apr 2020
Schmerer Matthew W, Abrams A Jeanine, Seby Sandra, Thomas Jesse C, Cartee John, Lucking Sean, Vidyaprakash Eshaw, Pham Cau D, Sharpe Samera, Pettus Kevin, St Cyr Sancta B, Torrone Elizabeth A, Kersh Ellen N, Gernert Kim M
Abstract excerpt
In 2016, the proportion of Neisseria gonorrhoeae isolates with reduced susceptibility to azithromycin rose to 3.6%. A phylogenetic analysis of 334 N. gonorrhoeae isolates collected in 2016 revealed a single, geographically diverse lineage of isolates with MICs of 2 to 16 μg/ml that carried a mosaic-like mtr locus, whereas the majority of isolates with MICs of ≥16 μg/ml appeared sporadically and carried 23S rRNA...
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