WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014.

doi:10.1093/jac/dkw279

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Article

WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014.

The Journal of antimicrobial chemotherapy - 1 Nov 2016

Jacobsson Susanne, Golparian Daniel, Cole Michelle, Spiteri Gianfranco, Martin Irene, Bergheim Thea, Borrego Maria José, Crowley Brendan, Crucitti Tania, Van Dam Alje P, Hoffmann Steen, Jeverica Samo, Kohl Peter, Mlynarczyk-Bonikowska Beata, Pakarna Gatis, Stary Angelika, Stefanelli Paola, Pavlik Peter, Tzelepi Eva, Abad Raquel, Harris Simon R, Unemo Magnus

Abstract excerpt

OBJECTIVES: To elucidate the genome-based epidemiology and phylogenomics of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae strains collected in 2009-14 in Europe and clarify the azithromycin resistance mechanisms. METHODS: Seventy-five azithromycin-resistant (MIC 4 to >256 mg/L) N. gonorrhoeae isolates collected in 17 European countries during 2009-14 were examined using antimicrobial susceptibility...

Topics

Adolescent
Adult
Aged
Anti-Bacterial Agents
Azithromycin
Cluster Analysis
DNA, Bacterial
DNA, Ribosomal
Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Europe

Female

Genes, Bacterial

Genome, Bacterial

Genotype

Gonorrhea

Humans

Male

Microbial Sensitivity Tests

Source

Open in PubMed

Identifiers

PMID: 27432597
DOI: 10.1093/jac/dkw279

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