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Article

Differentially expressed downstream genes in cells with normal or mutated p53.

Oncology research - 1 Jan 2003

Xu Hao, El-Gewely M Raafat

Abstract excerpt

Mutations in p53 gene could lead to loss of function, negative complementation, or to gain-of-oncogenic functions, thus leading to the increase of tumorigenicity and invasiveness of cancer. This study focused on cancer-related p53 mutants, including A138T, C141Y, RI58L, G245C, and R248Q. Using a modified differential display technique, response profiles of plasmid-expressed wild-type as well as mutated p53, in...

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Source

Identifiers

PMID: 12725534
DOI: 10.3727/096504003108748456

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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