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Article

Chromosomal elements regulate gene activity and chromatin structure of the human serpin gene cluster at 14q32.1.

Molecular and cellular biology - 1 May 2003

Marsden Mark D, Fournier R E K

Abstract excerpt

The human serine protease inhibitor (serpin) gene cluster at 14q32.1 contains a number of genes that are specifically expressed in hepatic cells. Cell-specific enhancers have been identified in several of these genes, but elements involved in locus-wide gene and chromatin control have yet to be defined. To identify regulatory elements in this region, we prepared a series of mutant chromosomal alleles by...

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Identifiers

PMID: 12724410
DOI: 10.1128/MCB.23.10.3516-3526.2003
PMCID: PMC164764

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