Article
The malignant clone in Waldenstrom's macroglobulinemia.
Seminars in oncology - 1 Apr 2003
Kriangkum Jitra, Taylor Brian J, Mant Michael J, Treon Steven P, Belch Andrew R, Pilarski Linda M
Abstract excerpt
The unique IgM VDJ sequence that characterizes the malignant clone in Waldenstrom's macroglobulinemia (WM), termed clonotypic, was identified for 12 WM patients. The majority of WM patients (92%) had a clonotypic IgM from the VH3 family, with predominantly long CDR3 regions, characteristic of tho...
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