Article
Antibodies in human sera specific to hypervariable region 1 of hepatitis C virus can block viral attachment.
Virology - 20 Apr 1995
Zibert A, Schreier E, Roggendorf M
Abstract excerpt
It has been postulated that antibodies specific to the hypervariable region 1 (HVR1) within the putative envelop protein E2 of hepatitis C virus (HCV) can neutralize virus. We studied such antibodies in sera of patients who were infected in a single-source outbreak by a contaminated anti-D immuno...
Topics
- Amino Acid Sequence
- Antibody Specificity
- Base Sequence
- Cells, Cultured
- Cloning, Molecular
- Disease Outbreaks
- Drug Contamination
- Epitopes
- Escherichia coli
- Fibroblasts
- Genetic Variation
- Hepacivirus
- Hepatitis Antibodies
- Hepatitis C
- Hepatitis C Antibodies
- Humans
- Molecular Sequence Data
- Neutralization Tests