Article
The power and statistical behaviour of allele-sharing statistics when applied to models with two disease loci.
Journal of genetics - 1 Dec 2002
Shugart Yin Y, Feng Bing-Jian, Collins Andrew
Abstract excerpt
We have evaluated the power for detecting a common trait determined by two loci, using seven statistics, of which five are implemented in the computer program SimWalk2, and two are implemented in GENEHUNTER. Unlike most previous reports which involve evaluations of the power of allele-sharing statistics for a single disease locus, we have used a simulated data set of general pedigrees in which a two-locus disease...
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