Article
Restricted dog leucocyte antigen (DLA) class II haplotypes and genotypes in Beagles.
Veterinary journal (London, England : 1997) - 1 Mar 2015
Soutter Francesca, Kennedy Lorna J, Ollier William E R, Solano-Gallego Laia, Catchpole Brian
Abstract excerpt
Beagles are commonly used in vaccine trials as part of the regulatory approval process. Genetic restriction within this breed and the impact this might have on vaccine responses are rarely considered. This study was designed to characterise diversity of dog leucocyte antigen (DLA) class II genes in a breeding colony of laboratory Beagles, whose offspring are used in vaccine studies. DLA haplotypes were determined...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
