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Article

The apolipoprotein E epsilon4 allele and the response to tacrine therapy in Alzheimer's disease.

European journal of neurology - 1 May 2000

Rigaud A S, Traykov L, Caputo L, Guelfi M C, Latour F, Couderc R, Moulin F, de Rotrou J, Forette F, Boller F

Abstract excerpt

The objective of our study was to evaluate the effects of the apolipoprotein E (ApoE) phenotype and gender on the response to tacrine treatment in Alzheimer's disease (AD). ApoE phenotyping was performed on 76 patients treated with tacrine for AD. This group comprised 33 ApoE epsilon4 allele carriers (epsilon4+) and 43 non-epsilon4 carriers (epsilon4-). Patients were treated blindly in relation to the ApoE...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10886308
DOI: 10.1046/j.1468-1331.2000.00073.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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