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Article

T lymphocytes infiltrating the liver during chronic hepatitis C infection express a broad range of T-cell receptor beta chain diversity.

Journal of hepatology - 1 May 2003

Vigan Ines, Jouvin-Marche Evelyne, Leroy Vincent, Pernollet Martine, Tongiani-Dashan Stefania, Borel Eve, Delachanal Elisabeth, Colomb Maurice, Zarski Jean-Pierre, Marche Patrice N

Abstract excerpt

BACKGROUND/AIMS: During viral chronic hepatitis C (CHC), the intra-hepatic lymphocyte infiltrate is mainly composed of T lymphocytes expressing alphabeta T-cell receptors (TCR). Since little is known about the TCRalphabeta diversity of intra-hepatic T lymphocytes (IHL), we evaluated the IHL repertoire from CHC patients (n=8) as compared to healthy subjects (n=4), total peripheral blood mononuclear cells, and...

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Identifiers

PMID: 12713877
DOI: 10.1016/s0168-8278(03)00089-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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