Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effects of hepatitis B virus core promoter mutations on hepatitis B core antigen distribution in hepatocytes as detected by laser-assisted microdissection.

Journal of hepatology - 1 May 2003

Kawai Keiko, Horiike Norio, Michitaka Kojiro, Onji Morikazu

Abstract excerpt

BACKGROUND/AIMS: The severity of liver damage in patients with chronic hepatitis B is dependent on several factors such as subcellular localization of hepatitis B core antigen (HBcAg) and mutation of hepatitis B virus (HBV) DNA. Here we studied the interrelationship between these two factors both in situ and in vitro. METHODS: Hepatocytes from liver biopsies showing expression of HBcAg only in the cytoplasm...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoplasm
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B Core Antigens

Share to Hepatitis B virus

Share to Hepatocytes

Share to Lasers

Share to Microdissection

Source

Identifiers

PMID: 12713875
DOI: 10.1016/s0168-8278(03)00031-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effects of hepatitis B virus core promoter mutations on hepatitis B core antigen distribution in hepatocytes as detected by laser-assisted microdissection.PMID 12713875Read ↗

Hepatitis B virus basal core promoter mutation and DNA load correlate with expression of hepatitis B core antigen in patients with chronic hepatitis B.Semantic proximity Read ↗

Impact of precore and core promoter mutations on hepatic histology in patients with chronic hepatitis B.Semantic proximity Read ↗

Mutations in the core promoter region of hepatitis B virus in patients with chronic hepatitis B.Semantic proximity Read ↗

Cytoplasmic expression of hepatitis B core antigen in chronic hepatitis B virus infection: role of precore stop mutants.Semantic proximity Read ↗

Hepatitis B viral core protein disrupts human host gene expression by binding to promoter regionsSemantic proximity Read ↗

Immunopathology on hepatocyte expression of HBV surface, core, and x antigens in chronic hepatitis B: clinical and virological correlation.Semantic proximity Read ↗

Intracellular distribution of hepatitis B virus core protein expressed in vitro depends on the sequence of the isolate and the serologic pattern.Semantic proximity Read ↗

Differentiation of core gene products of the hepatitis B virus in infected liver tissue using monoclonal antibodies.Semantic proximity Read ↗

The role of mutations in core protein of hepatitis B virus in liver fibrosis.Semantic proximity Read ↗

In situ detection of mutated hepatitis B virus in microdissected, formalin-fixed liver tissues from patients with chronic hepatitis B.Semantic proximity Read ↗

Multiple liver-specific factors bind to the hepatitis B virus core/pregenomic promoter: trans-activation and repression by CCAAT/enhancer binding protein.Semantic proximity Read ↗

Hepatitis B virus mutations associated with in situ expression of hepatitis B core antigen, viral load and prognosis in chronic hepatitis B patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.