Article
Using a database of HIV patients undergoing genotypic resistance test after HAART failure to understand the dynamics of M184V mutation.
Antiviral therapy - 1 Feb 2003
Zaccarelli Mauro, Perno Carlo Federico, Forbici Federica, Cingolani Antonella, Liuzzi Guiseppina, Bertoli Ada, Trotta Maria Paola, Bellocchi Maria Concetta, Di Giambenedetto Simona, Tozzi Valerio, Gori Caterina, D'Arrigo Roberta, De Longis Patrizio, Noto Pasquale, Girardi Enrico, De Luca Andrea, Antinori Andrea
Abstract excerpt
OBJECTIVE: M184V/I mutation is associated with high-level phenotypic resistance to lamivudine (3TC). The aim of the present analysis was to correlate the time of appearance/disappearance of M184V/I with duration of 3TC treatment. METHODS: Overall, 211 patients were selected from a database of HIV patients undergoing genotypic resistance test after virological failure of HAART regimens in two major reference...
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