High prevalence of M184 mutation among patients with viroimmunologic discordant responses to highly active antiretroviral therapy and outcomes after change of therapy guided by genotypic analysis.

doi:10.1128/JCM.41.7.3007-3012.2003

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Article

High prevalence of M184 mutation among patients with viroimmunologic discordant responses to highly active antiretroviral therapy and outcomes after change of therapy guided by genotypic analysis.

Journal of clinical microbiology - 1 Jul 2003

Nicastri Emanuele, Sarmati Loredana, d'Ettorre Gabriella, Parisi Saverio G, Palmisano Lucia, Galluzzo Clementina, Montano Marco, Uccella Ilaria, Amici Roberta, Gatti Francesca, Vullo Vincenzo, Concia Ercole, Vella Stefano, Andreoni Massimo

Abstract excerpt

Whether highly active antiretroviral therapy (HAART) should be modified in patients with persistent increases in CD4(+) T cells despite detectable viral loads is an unresolved question. Forty-three heavily pretreated human immunodeficiency virus (HIV)-infected patients with virologic failure during HAART were studied before a change of therapy guided by genotypic analysis and during follow-up. Patients with an...

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Identifiers

PMID: 12843034
DOI: 10.1128/JCM.41.7.3007-3012.2003
PMCID: PMC165358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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