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Article

High-resolution SNP scan of chromosome 6p21 in pooled samples from patients with complex diseases.

Genomics - 1 May 2003

Herbon Nicole, Werner Monika, Braig Christine, Gohlke Henning, Dütsch Gaby, Illig Thomas, Altmüller Janine, Hampe Jochen, Lantermann Annette, Schreiber Stefan, Bonifacio Ezio, Ziegler Annette, Schwab Sibylle, Wildenauer Dieter, van den Boom Dirk, Braun Andreas, Knapp Michael, Reitmeir Peter, Wjst Matthias

Abstract excerpt

We apply a high-throughput protocol of chip-based mass spectrometry (matrix-assisted laser desorption/ionization time-of-flight; MALDI-TOF) as a method of screening for differences in single-nucleotide polymorphism (SNP) allele frequencies. Using pooled DNA from individuals with asthma, Crohn's disease (CD), schizophrenia, type 1 diabetes (T1D), and controls, we selected 534 SNPs from an initial set of 1435 SNPs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 6

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Source

Identifiers

PMID: 12706109
DOI: 10.1016/s0888-7543(02)00035-6

Genes

LTA
MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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