Article
Mutations disrupting the ordering and topographic mapping of axons in the retinotectal projection of the zebrafish, Danio rerio.
Development (Cambridge, England) - 1 Dec 1996
Trowe T, Klostermann S, Baier H, Granato M, Crawford A D, Grunewald B, Hoffmann H, Karlstrom R O, Meyer S U, Müller B, Richter S, Nüsslein-Volhard C, Bonhoeffer F
Abstract excerpt
Retinal ganglion cells connect to their target organ, the rectum, in a highly ordered fashion. We performed a large-scale screen for mutations affecting the retinotectal projection of the zebrafish, which resulted in the identification of 114 mutations. 44 of these mutations disturb either the order of RGC axons in the optic nerve and tract, the establishment of a topographic map on the tectum, or the formation...
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