Article
Mutations disrupting the ordering and topographic mapping of axons in the retinotectal projection of the zebrafish, Danio rerio.
Development (Cambridge, England) - 1 Dec 1996
Trowe T, Klostermann S, Baier H, Granato M, Crawford A D, Grunewald B, Hoffmann H, Karlstrom R O, Meyer S U, Müller B, Richter S, Nüsslein-Volhard C, Bonhoeffer F
Abstract excerpt
Retinal ganglion cells connect to their target organ, the rectum, in a highly ordered fashion. We performed a large-scale screen for mutations affecting the retinotectal projection of the zebrafish, which resulted in the identification of 114 mutations. 44 of these mutations disturb either the or...
Topics
- Animals
- Axons
- Brain Mapping
- Gene Expression Regulation, Developmental
- Mutation
- Phenotype
- Retina
- Superior Colliculi
- Visual Pathways
- Zebrafish
