Article
Genetic control of serum IgE levels: a study of low molecular weight protein tyrosine phosphatase.
Clinical genetics - 1 Mar 2003
Bottini N, Otsu A, Borgiani P, Saccucci P, Stefanini L, Greco E, Fontana L, Hopkins J M, Mao X-Q
Abstract excerpt
Protein tyrosine phosphatases (PTPases) have recently been recognized as important modulators of various signal transduction pathways in immune cells. Genetic polymorphisms have been described in genes codifying for members of this family of enzymes, and the genetics of PTPases is predicted to play an important role in the etiology of immune diseases and of their clinical variability. The low molecular weight...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.