Article
Allergy and ACP1 genetic polymorphism.
Allergy and asthma proceedings - 1 Jan 2000
Bottini Egidio, Bergamaschi Antonio, Magrini Andrea, Spina Claudio, Ammendola Leonardo, Grassi Saverio, Bottini Nonzio, Gloria-Bottini Fulvia
Abstract excerpt
The ACP1 (acid phosphatase locus 1) gene encodes a highly polymorphic low molecular weight protein tyrosine phosphatase (LMPTP) involved in the modulation of various signal transduction pathways including T-cell receptor. Previous studies suggest an association of this enzyme with allergic disorders. The aim of this study was to review our previous data and to confirm the association by further observations. Two...
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