Article
Identification of D19S246 as a novel lung adenocarcinoma susceptibility locus by genome survey with 10-cM resolution microsatellite markers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2003
Yanagitani Noriko, Kohno Takashi, Kim Jeong-Gyoon, Kunitoh Hideo, Tamura Tomohide, Takei Yoshikazu, Tsuchiya Satoshi, Saito Ryusei, Yokota Jun
Abstract excerpt
Adenocarcinoma is now the most common histological subtype of lung cancer;however, genetic factors that affect cancer susceptibility are largely unknown. In this study, we performed a systematic survey of the human genome with an average resolution of 10 cM to identify loci that could help us target novel risk genes for lung adenocarcinoma using linkage disequilibrium. Genotyping of DNA "pools" from 100 lung...
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