Article
A multi-laboratory characterization of the KIR genotypes of 10th International Histocompatibility Workshop cell lines.
Human immunology - 1 May 2003
Cook Mark A, Norman Paul J, Curran Martin D, Maxwell Lynn D, Briggs David C, Middleton Derek, Vaughan Robert W
Abstract excerpt
Killer immunoglobulinlike receptors (KIRs) are expressed on natural killer and T cells. Both inhibitory and noninhibitory forms have been described, leading to inhibition or continuation of cellular killing activity. The natural ligands identified so far of KIRs are class I human leukocyte antigens (HLA). In particular, the interaction of some KIRs with HLA-Cw has been well characterized. Recent work has...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
