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The distribution of 13 killer‐cell immunoglobulin‐like receptor loci in UK blood donors from three ethnic groups

1 Jun 2003

Abstract excerpt

Killer-cell immunoglobulin-like receptors (KIRs) can inhibit the killing activity of natural killer (NK) cells if they interact with their ligand, class I HLA. Using a modified polymerase chain reaction-sequence-specific primers (PCR-SSP) method for typing KIRs using genomic DNA, we compared KIR frequencies in three ethnic populations drawn from UK blood donors. We found a significantly lower frequency of the...

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PMID: 12787000
DOI: 10.1046/j.1365-2370.2003.00394.x

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