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Article

Strain-specific differences in the expression and activity of Ogg1 in the CNS.

Gene expression - 1 Jan 2003

Mosquera Diana I, Stedeford Todd, Cardozo-Pelaez Fernando, Sanchez-Ramos Juan

Abstract excerpt

The expression and activity of 8-oxoguanosine DNA-glycosylase (Ogg1), a key enzyme responsible forthe clearance of the oxidized DNA base 8-hydroxy-2'-deoxyguanosine (oxo8dG), was determined in the cerebellum (CB) and the caudate and the putamen (CP) of male Balb/c, ICR, and C57BL/J mice. There was no significant difference in the protein expression of Ogg1 in the CB or CP. The activity of Ogg1 was not...

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Identifiers

PMID: 12691525
DOI: 10.3727/000000003783992333
PMCID: PMC5991156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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