Article
Genotypic differences in central neurotransmitter responses to aging in mice.
Neurobiology of aging - 1 Jan 2000
Ebel A, Strosser M T, Kempf E
Abstract excerpt
Dopamine, serotonin, cholinergic and somatostatin responses to aging have been followed in striatum and hippocampus of two inbred strains of mice (C57BL and BALB/c). A striking strain dependency is noted. Dopaminergic mechanisms in BALB/c mice become particularly defective in striatum where both dopamine release and dopamine turnover are affected. Also, striatal cholinergic activity and somatostatin levels are...
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