Article
Ethnic variation in the clinical manifestations of rheumatoid arthritis: role of HLA-DRB1 alleles.
Arthritis and rheumatism - 15 Apr 2003
Del Rincón Inmaculada, Battafarano Daniel F, Arroyo Ramón A, Murphy Frederick T, Fischbach Michael, Escalante Agustín
Abstract excerpt
OBJECTIVE: To assess the extent of ethnic variation in the clinical expression of rheumatoid arthritis (RA) and the role of HLA-DRB1 alleles in this variation. METHODS: We assessed consecutive RA patients for joint findings, subcutaneous nodules, laboratory and radiographic findings, and treatment. We typed HLA-DRB1 alleles to identify those that contain the shared epitope (SE). We adjusted ethnic comparisons for...
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