Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inheritance of the shared epitope and long-term outcomes of rheumatoid arthritis among community-based Caucasian females.

Genetic epidemiology - 1 Jan 1998

Criswell L A, Mu H, Such C L, King M C

Abstract excerpt

Multiple HLA-DRB1 alleles encoding a shared epitope (SE) at amino acid positions 70-74 are associated with susceptibility and severity of rheumatoid arthritis (RA). We examined the relationship between the number and DRB1 genotype of SE alleles inherited and long-term outcomes of 180 community-based, Caucasian female RA patients followed annually for up to 12 years. Outcomes examined were physician assessment of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Arthritis, Rheumatoid
Share to Epitopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Genetic Heterogeneity

Share to Genotype

Share to Models, Genetic

Share to White People

Source

Identifiers

PMID: 9523211
DOI: 10.1002/(SICI)1098-2272(1998)15:1<61::AID-GEPI5>3.0.CO;2-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inheritance of the shared epitope and long-term outcomes of rheumatoid arthritis among community-based Caucasian females.PMID 9523211Read ↗

Relative predispositional effects and mode of inheritance of HLA-DRB1 alleles among community-based Caucasian females with rheumatoid arthritis.Semantic proximity Read ↗

Heterogeneity between men and women in the influence of the HLA-DRB1 shared epitope on the clinical expression of rheumatoid arthritis.Semantic proximity Read ↗

Ethnic variation in the clinical manifestations of rheumatoid arthritis: role of HLA-DRB1 alleles.Semantic proximity Read ↗

HLA-DRB1 genotype associations in 793 white patients from a rheumatoid arthritis inception cohort: frequency, severity, and treatment bias.Semantic proximity Read ↗

Lack of association of the HLA-DRB1 shared epitope with rheumatoid nodules: an individual patient data meta-analysis of 3,272 Caucasian patients with rheumatoid arthritis.Semantic proximity Read ↗

Value of the HLA-DRB1 shared epitope for predicting radiographic damage in rheumatoid arthritis depends on the individual patient risk profile.Semantic proximity Read ↗

Association of DRB1 shared epitope genotypes with early mortality in rheumatoid arthritis: results of eighteen years of followup from the early rheumatoid arthritis study.Semantic proximity Read ↗

Sex influences on the penetrance of HLA shared-epitope genotypes for rheumatoid arthritis.Semantic proximity Read ↗

The genotypic distribution of shared-epitope DRB1 alleles suggests a recessive mode of inheritance of the rheumatoid arthritis disease-susceptibility gene.Semantic proximity Read ↗

Familial seropositive rheumatoid arthritis in North American Native families: effects of shared epitope and cytokine genotypes.Semantic proximity Read ↗

Reshaping the shared epitope hypothesis: HLA-associated risk for rheumatoid arthritis is encoded by amino acid substitutions at positions 67-74 of the HLA-DRB1 molecule.Semantic proximity Read ↗

Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.