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Article

Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos.

Developmental biology - 15 Apr 2003

Kawamura Kazuhiro, Sato Naoki, Fukuda Jun, Kodama Hideya, Kumagai Jin, Tanikawa Hideo, Shimizu Yasushi, Tanaka Toshinobu

Abstract excerpt

Apoptosis is an essential physiologic process used in almost all tissues to remove damaged or superfluous cells. However, the early embryos are unique because no cell death is found up to the blastocyst stage during normal development. Survivin, a member of the IAP family, is capable of binding to caspases to modulate their functions. Here, we investigated the expression of survivin, and its role in preventing...

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Source

Identifiers

PMID: 12679106
DOI: 10.1016/s0012-1606(02)00135-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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