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Article

A high level of integrin α6 expression in human intrahepatic cholangiocarcinoma cells is associated with a migratory and invasive phenotype.

Digestive diseases and sciences - 1 Jun 2013

Ding Yan-bing, Deng Bin, Huang You-sheng, Xiao Wei-ming, Wu Jian, Zhang Yan-qing, Wang Yuan-zhi, Wu Da-cheng, Lu Guo-tao, Wu Ke-yan

Abstract excerpt

BACKGROUND: The integrin α6 subunit is part of the integrin α6β1 and α6β4 complexes, which are known to mediate the invasion of carcinoma cells. However, the precise role of integrin α6 in intrahepatic cholangiocarcinoma (ICC) has not yet been addressed. METHODS: Twenty cases of ICCs and matched nontumor samples were used to analyze integrin α6 expression by immunohistochemistry. After the expression of integrin...

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Identifiers

PMID: 23306848
DOI: 10.1007/s10620-012-2524-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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