Article
Alterations in metastatic properties of hepatocellular carcinoma cell following H-ras oncogene transfection.
World journal of gastroenterology - 1 Jun 2001
Wang Q, Lin Z Y, Feng X L
Abstract excerpt
AIM: To demonstrate the relationship between H-ras oncogene and hepatocellular carcinoma (HCC) metastasis. METHODS: Activated H-ras oncogene was transfected into SMMC 7721, a cell line derived from human HCC, by calcium phosphate transfection method. Some metastasis-related parameters were detected in vitro, including adhesion assay, migration assay, expression of collagenase IV(c IV ase) and epidermal growth...
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