Article
Expression of the integrin alpha5 subunit and its mediated cell adhesion in hepatocellular carcinoma.
Journal of cancer research and clinical oncology - 1 Jan 1997
Yao M, Zhou X D, Zha X L, Shi D R, Fu J, He J Y, Lu H F, Tang Z Y
Abstract excerpt
Tumor invasion and metastasis are complex processes, requiring the ability of tumor cells to interact with proteins of the extracellular matrix through cell-adhesion molecules on the cell surface. Integrins are heterodimeric membrane glycoproteins, consisting of alpha and beta subunits, which ena...
Topics
- Antigens, CD
- Carcinoma, Hepatocellular
- Cell Adhesion
- Fibronectins
- Humans
- Integrin alpha5
- Liver Neoplasms
- Neoplasm Metastasis
- Phenotype
- Polymerase Chain Reaction
- RNA, Messenger
- Receptors, Fibronectin
- Tumor Cells, Cultured
