Article
Expression of the integrin alpha5 subunit and its mediated cell adhesion in hepatocellular carcinoma.
Journal of cancer research and clinical oncology - 1 Jan 1997
Yao M, Zhou X D, Zha X L, Shi D R, Fu J, He J Y, Lu H F, Tang Z Y
Abstract excerpt
Tumor invasion and metastasis are complex processes, requiring the ability of tumor cells to interact with proteins of the extracellular matrix through cell-adhesion molecules on the cell surface. Integrins are heterodimeric membrane glycoproteins, consisting of alpha and beta subunits, which enable cells to recognize adhesive substrates in the extracellular matrix. The roles of the integrin alpha5beta1 in tumor...
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