Article
Predicting mutation frequencies in stem-loop structures of derepressed genes: implications for evolution.
Molecular microbiology - 1 Apr 2003
Wright Barbara E, Reschke Dennis K, Schmidt Karen H, Reimers Jacqueline M, Knight William
Abstract excerpt
This work provides evidence that, during transcription, the mutability (propensity to mutate) of a base in a DNA secondary structure depends both on the stability of the structure and on the extent to which the base is unpaired. Zuker's DNA folding computer program reveals the most probable stem-...
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