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Article

Expression of enhancing factor/phospholipase A2 in skin results in abnormal epidermis and increased sensitivity to chemical carcinogenesis.

Oncogene - 3 Apr 2003

Mulherkar Rita, Kirtane Bhakti M, Ramchandani Asha, Mansukhani Nirmala P, Kannan Sadhana, Naresh Kikkeri N

Abstract excerpt

Enhancing factor (EF), a growth factor modulator, is the mouse homologue of human secretory group II phospholipase A(2). EF exhibits growth-promoting activity in vitro, in the presence of epidermal growth factor, and also brings about phenotypic transformation of normal cells. In order to ascertain the role of EF in vivo, a human keratin-14 promoter was used to drive the expression of EF ectopically to squamous...

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Identifiers

PMID: 12673199
DOI: 10.1038/sj.onc.1206229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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