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THE BIOLOGY OF THE GROWTH PLATE

1 Apr 2003

Abstract excerpt

• Chondrocytes in the growth plate undergo a complex series of molecular, biochemical, and morphological changes during the process of differentiation. • Longitudinal growth depends on both proliferation and hypertrophy of chondrocytes in the growth plate. • Integrated growth factor signaling pathways control the key transition between proliferation and hypertrophy that is required for completion of the...

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PMID: 12672851
DOI: 10.2106/00004623-200304000-00021

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