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Article

Physiology and pathophysiology of the growth plate.

Birth defects research. Part C, Embryo today : reviews - 1 May 2003

Ballock R Tracy, O'Keefe Regis J

Abstract excerpt

Longitudinal growth of the skeleton is a result of endochondral ossification that occurs at the growth plate. Through a sequential process of cell proliferation, extracellular matrix synthesis, cellular hypertrophy, matrix mineralization, vascular invasion, and eventually apoptosis, the cartilage model is continually replaced by bone as length increases. The regulation of longitudinal growth at the growth plate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12955857
DOI: 10.1002/bdrc.10014

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