Article
Extracellular matrix and developing growth plate.
Current osteoporosis reports - 1 Dec 2014
Myllyharju Johanna
Abstract excerpt
Growth plate is a specialized cartilaginous structure that mediates the longitudinal growth of skeletal bones. It consists of ordered zones of chondrocytes that secrete an extracellular matrix (ECM) composed of specific types of collagens and proteoglycans. Several heritable human skeletal dysplasias are caused by mutations in these ECM components and this review focuses on the roles of type II, IX, X, and XI...
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