Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p38 MAPK is involved in activin A- and hepatocyte growth factor-mediated expression of pro-endocrine gene neurogenin 3 in AR42J-B13 cells.

The Journal of biological chemistry - 13 Jun 2003

Ogihara Takeshi, Watada Hirotaka, Kanno Rei, Ikeda Fuki, Nomiyama Takashi, Tanaka Yasushi, Nakao Atsuhito, German Michael S, Kojima Itaru, Kawamori Ryuzo

Abstract excerpt

Neurogenin3 (ngn3) is a transcription factor that is essential for the differentiation of pancreatic endocrine cells. To investigate the signaling pathway that regulates ngn3 expression, we used AR42J-B13 cells as a model of the differentiation of pancreatic islets. In these cells, treatment with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Activins
Share to Basic Helix-Loop-Helix Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme Inhibitors

Share to Hepatocyte Growth Factor

Share to Islets of Langerhans

Share to Luciferases

Share to Mitogen-Activated Protein Kinases

Share to p38 Mitogen-Activated Protein Kinases

Source

Identifiers

PMID: 12670941
DOI: 10.1074/jbc.M302684200

Genes

HGF
NEUROG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12670941-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p38 MAPK is involved in activin A- and hepatocyte growth factor-mediated expression of pro-endocrine gene neurogenin 3 in AR42J-B13 cells.PMID 12670941Read ↗

Regulation of the Pancreatic Pro-Endocrine Gene <i>Neurogenin3</i>Semantic proximity Read ↗

Neurogenin3 Activates the Islet Differentiation Program while Repressing Its Own ExpressionSemantic proximity Read ↗

Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.Semantic proximity Read ↗

Defining Pancreatic Endocrine Precursors and Their DescendantsSemantic proximity Read ↗

Neurogenin3 Cooperates with Foxa2 to Autoactivate Its Own ExpressionSemantic proximity Read ↗

Identification of the bHLH Factor Math6 as a Novel Component of the Embryonic Pancreas Transcriptional NetworkSemantic proximity Read ↗

The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas.Semantic proximity Read ↗

Transcription Factor Hepatocyte Nuclear Factor 6 Regulates Pancreatic Endocrine Cell Differentiation and Controls Expression of the Proendocrine Gene <i>ngn3</i>Semantic proximity Read ↗

Regulation of Pancreatic microRNA-7 ExpressionSemantic proximity Read ↗

Glis3 Regulates Neurogenin 3 Expression in Pancreatic β-Cells and Interacts with Its Activator, Hnf6Semantic proximity Read ↗

Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3.Semantic proximity Read ↗

Neurogenin3 and hepatic nuclear factor 1 cooperate in activating pancreatic expression of Pax4.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.