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Article

Activation of the complement cascade by Bordetella pertussis.

FEMS microbiology letters - 28 Mar 2003

Barnes Michael G, Weiss Alison A

Abstract excerpt

Bordetella pertussis must survive the defenses of the human respiratory tract including the complement system. The BrkA (Bordetella resistance to killing) protein prevents killing by the antibody-dependent classical pathway. In this study, the ability of B. pertussis to activate the human complement cascade by other pathways was examined. B. pertussis was not killed in serum depleted of C2, however serum depleted...

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PMID: 12670691
DOI: 10.1016/S0378-1097(03)00132-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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