Article
Inhibition of hepatitis B virus expression and replication by RNA interference.
Hepatology (Baltimore, Md.) - 1 Apr 2003
Shlomai Amir, Shaul Yosef
Abstract excerpt
RNA interference (RNAi) is the process of sequence-specific gene silencing, initiated by double-stranded RNA (dsRNA) that is homologous in sequence to the target gene. Because it has been shown that RNAi can be accomplished in cultured mammalian cells by introducing small interfering RNAs (siRNAs), much effort has been invested in exploiting this phenomenon for experimental and therapeutic means. In this study,...
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