Article
Electrostatic contributions to the stability of a thermophilic cold shock protein.
Biophysical journal - 1 Apr 2003
Zhou Huan-Xiang, Dong Feng
Abstract excerpt
The thermophilic Bacillus caldolyticus cold shock protein (Bc-Csp) differs from the mesophilic Bacillus subtilis cold shock protein B (Bs-CspB) in 11 of the 66 residues. Stability measurements of Schmid and co-workers have implicated contributions of electrostatic interactions to the thermostability. To further elucidate the physical basis of the difference in stability, previously developed theoretical methods...
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