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Article

Variation within genes encoding interleukin-1 and the interleukin-1 receptor antagonist influence the severity of meningococcal disease.

Annals of internal medicine - 1 Apr 2003

Read Robert C, Cannings Chris, Naylor Simone C, Timms Janine M, Maheswaran Ravi, Borrow Raymond, Kaczmarski Edward B, Duff Gordon W

Abstract excerpt

BACKGROUND: Genetically determined variation in proinflammatory cytokine release influences severity of meningococcal disease and other serious infections. OBJECTIVE: To ascertain the relative frequencies of single nucleotide polymorphisms within the interleukin-1 gene locus among patients who survived and those who died of meningococcal disease and a control population of blood donors. DESIGN: Association study....

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Source

Identifiers

PMID: 12667023
DOI: 10.7326/0003-4819-138-7-200304010-00009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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