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Article

Severity of meningococcal disease associated with genomic bacterial load.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Mar 2009

Darton Tom, Guiver Malcolm, Naylor Simone, Jack Dominic L, Kaczmarski Edward B, Borrow Raymond, Read Robert C

Abstract excerpt

BACKGROUND: Diagnostic polymerase chain reaction (PCR) detection of Neisseria meningitidis has enabled accurate quantification of the bacterial load in patients with meningococcal disease. METHODS: Quantification of the N. meningitidis DNA level by real time-PCR was conducted on whole-blood samples obtained from patients presenting with meningococcal disease to hospitals throughout England and Wales over a 3-year...

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PMID: 19191644
DOI: 10.1086/596707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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