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Article

Genomic polymorphic profiles in an Irish population with meningococcaemia: is it possible to predict severity and outcome of disease?

Genes and immunity - 1 Dec 2003

Balding J, Healy C M, Livingstone W J, White B, Mynett-Johnson L, Cafferkey M, Smith O P

Abstract excerpt

Patients with meningococcal disease have increased plasma levels of proinflammatory cytokines IL-6, IL-1beta, and TNF-alpha, with higher levels associated with fatal outcome. This study investigated whether polymorphisms in genes encoding these cytokines, and in those encoding anti-inflammatory I...

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Source

Identifiers

PMID: 14647192
DOI: 10.1038/sj.gene.6364020

Genes

TNF
LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14647192-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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