Annexin A5 is not essential for skeletal development.

doi:10.1128/MCB.23.8.2907-2913.2003

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Article

Annexin A5 is not essential for skeletal development.

Molecular and cellular biology - 1 Apr 2003

Brachvogel Bent, Dikschas Jörg, Moch Helga, Welzel Heike, von der Mark Klaus, Hofmann Clementine, Pöschl Ernst

Abstract excerpt

Annexins are highly conserved proteins that are characterized by their ability to interact with phospholipids in a calcium-dependent manner. Although diverse functions have been ascribed to annexins based on in vitro analyses, their in vivo functions still remain unclear. The intensively studied annexin A5 has been identified by its effects on blood coagulation, and subsequently, its function as a...

Topics

Animals
Animals, Newborn
Annexin A5
Annexins
Bone Development
Calcification, Physiologic
Chondrocytes
Gene Targeting
Immunohistochemistry
In Vitro Techniques
Mice
Mice, Inbred C57BL
Mice, Knockout
Phenotype

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Identifiers

PMID: 12665588
DOI: 10.1128/MCB.23.8.2907-2913.2003
PMCID: PMC152556

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