Article
Autoimmune hair loss induced by alloantigen in C57BL/6 mice.
Cell structure and function - 1 Feb 2003
Zong Zhi-ping, Matsui Shinobu, Li Ai-li, Katsuda Shogo, Yamaguchi Nobuo
Abstract excerpt
Exponentially growing Meth-A cells expressing H-2K(d).D (d) antigen were found to induce alopecia when injected intraperitoneally into normal C57BL/6 mice, which express the H-2K(b).D (b) antigen. However, the capacity to induce alopecia disappeared when Meth-A cells were treated with K252a, which inhibits protein kinases. Histologically, skin in affected areas showed dense mononuclear cell infiltration and a...
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