Article
An Escherichia coli MG1655 lipopolysaccharide deep-rough core mutant grows and survives in mouse cecal mucus but fails to colonize the mouse large intestine.
Infection and immunity - 1 Apr 2003
Møller Annette K, Leatham Mary P, Conway Tyrrell, Nuijten Piet J M, de Haan Louise A M, Krogfelt Karen A, Cohen Paul S
Abstract excerpt
The ability of E. coli strains to colonize the mouse large intestine has been correlated with their ability to grow in cecal and colonic mucus. In the present study, an E. coli MG1655 strain was mutagenized with a mini-Tn5 Km (kanamycin) transposon, and mutants were tested for the ability to grow on agar plates with mouse cecal mucus as the sole source of carbon and nitrogen. One mutant, designated MD42 (for...
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