Article
Increased Listeria monocytogenes Dissemination and Altered Population Dynamics in Muc2-Deficient Mice.
Infection and immunity - 17 Mar 2021
Zhang Ting, Sasabe Jumpei, Hullahalli Karthik, Sit Brandon, Waldor Matthew K
Abstract excerpt
The mucin Muc2 is a major constituent of the mucus layer that covers the intestinal epithelium and creates a barrier between epithelial cells and luminal commensal or pathogenic microorganisms. The Gram-positive foodborne pathogen Listeria monocytogenes can cause enteritis and also disseminate from the intestine to give rise to systemic disease. L. monocytogenes can bind to intestinal Muc2, but the influence of...
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