Article
Glycogen and maltose utilization by Escherichia coli O157:H7 in the mouse intestine.
Infection and immunity - 1 Jun 2008
Jones Shari A, Jorgensen Mathias, Chowdhury Fatema Z, Rodgers Rosalie, Hartline James, Leatham Mary P, Struve Carsten, Krogfelt Karen A, Cohen Paul S, Conway Tyrrell
Abstract excerpt
Mutant screens and transcriptome studies led us to consider whether the metabolism of glucose polymers, i.e., maltose, maltodextrin, and glycogen, is important for Escherichia coli colonization of the intestine. By using the streptomycin-treated mouse model, we found that catabolism of the disaccharide maltose provides a competitive advantage in vivo to pathogenic E. coli O157:H7 and commensal E. coli K-12,...
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