Article
Metabolite profiling of Mycoplasma gallisepticum mutants, combined with bioinformatic analysis, can reveal the likely functions of virulence-associated genes.
Veterinary microbiology - 1 Sept 2018
Masukagami Yumiko, Nijagal Brunda, Tseng Chi-Wen, Dayalan Saravanan, Tivendale Kelly A, Markham Philip F, Browning Glenn F, Sansom Fiona M
Abstract excerpt
Mycoplasma gallisepticum is an economically important pathogen of commercial poultry. An improved understanding of M. gallisepticum pathogenesis is required to develop better control methods. We recently identified a number of M. gallisepticum mutants with defects in colonization and persistence in chickens using signature-tagged transposon mutagenesis. Loss of virulence was associated with mutations in a...
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