Roles of Fc receptors in autoimmunity

doi:10.1038/nri856

Article

Roles of Fc receptors in autoimmunity

1 Aug 2002

Abstract excerpt

The receptors for the Fc of immunoglobulins, Fc receptors (FcRs), link the humoral and cellular branches of the immune system, and they have important functions in the activation and down-modulation of immune responses. Balanced signalling through activating and inhibitory FcRs regulates the activity of various cells in the immune system. Recent work in animal models indicates that the development of many human...

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