Article
FcεRI-Toll-like receptor interaction in atopic dermatitis.
Current problems in dermatology - 1 Jan 2011
Novak Natalija, Bieber Thomas
Abstract excerpt
Exogenous factors such as allergens and microbial components play an important role as triggers of atopic dermatitis (AD). According to the current disease model, allergens as well as microbial antigens get into contact with surface receptors expressed by dendritic cells (DCs) in the skin of patients with AD. Allergen binding is most likely by the high-affinity receptor for IgE (FcεRI), which is highly expressed...
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