Article
Association of MSX1 and TGFB3 with nonsyndromic clefting in humans.
American journal of human genetics - 1 Aug 1998
Lidral A C, Romitti P A, Basart A M, Doetschman T, Leysens N J, Daack-Hirsch S, Semina E V, Johnson L R, Machida J, Burds A, Parnell T J, Rubenstein J L, Murray J C
Abstract excerpt
Nonsyndromic cleft lip with or without cleft palate (CL/P) and nonsyndromic cleft palate only (CPO) are common congenital anomalies with significant medical, psychological, social, and economic ramifications. Both CL/P and CPO are examples of complex genetic traits. There exists sufficient eviden...
Topics
- Amino Acid Substitution
- Case-Control Studies
- Cleft Lip
- Cleft Palate
- Exons
- Genetic Markers
- Genetic Variation
- Homeodomain Proteins
- Humans
- Introns
- Iowa
- Linkage Disequilibrium
- MSX1 Transcription Factor
- Mutation