Article
Influence of cytokine and mannose binding protein gene polymorphisms on human T-cell leukemia virus type I (hTLV-I) provirus load in HTLV-I asymptomatic carriers.
Human immunology - 1 Apr 2003
Nishimura Masataka, Maeda Michiyuki, Yasunaga Jun-ichiro, Kawakami Hideshi, Kaji Ryuji, Adachi Akio, Uchiyama Takashi, Matsuoka Masao
Abstract excerpt
Human T-cell leukemia virus type I (HTLV-I) provirus load differs more than 100-fold among carriers and a high provirus load in the peripheral blood mononuclear cells (PBMCs) is regarded as a risk factor for both preleukemic states and inflammatory diseases including HTLV-I-associated myelopathy (HAM). We examined polymorphisms in the genes for tumor necrosis factor (TNF), TNF receptor type 1 and 2, lymphotoxin...
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